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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
14.85
Human Site:
Y620
Identified Species:
29.7
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
Y620
S
E
E
E
K
L
K
Y
E
E
K
A
T
K
D
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
Y749
S
E
E
E
K
L
K
Y
E
E
K
A
T
K
D
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
I571
D
L
L
S
N
R
V
I
K
K
P
M
S
A
S
Dog
Lupus familis
XP_536002
930
105612
Y620
S
E
E
E
K
L
K
Y
E
E
K
A
T
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
Q595
S
Q
R
L
P
G
P
Q
S
T
S
A
A
E
V
Rat
Rattus norvegicus
NP_001009535
919
103710
D616
Y
E
E
K
A
K
K
D
L
E
R
Y
N
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
R607
R
P
G
S
A
G
T
R
S
L
L
G
G
R
R
Chicken
Gallus gallus
NP_001006508
916
103017
Y612
N
E
E
E
K
Q
E
Y
E
L
K
A
A
R
D
Frog
Xenopus laevis
NP_001079545
925
103654
A616
F
N
Y
E
E
K
A
A
K
D
L
E
R
Y
N
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
S608
G
E
G
K
K
Q
M
S
A
E
S
P
L
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
S474
V
A
I
S
N
Q
E
S
L
D
V
G
A
G
N
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
C631
P
F
S
A
Q
Q
I
C
S
T
L
Q
F
S
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
0
100
N.A.
13.3
26.6
N.A.
0
60
6.6
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
26.6
40
N.A.
6.6
80
33.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
17
0
9
9
9
0
0
42
25
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
0
17
0
0
0
0
34
% D
% Glu:
0
50
42
42
9
0
17
0
34
42
0
9
0
9
0
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
9
0
17
0
0
17
0
0
0
0
0
17
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
42
17
34
0
17
9
34
0
0
25
9
% K
% Leu:
0
9
9
9
0
25
0
0
17
17
25
0
9
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
17
0
0
0
0
0
0
0
9
17
17
% N
% Pro:
9
9
0
0
9
0
9
0
0
0
9
9
0
0
0
% P
% Gln:
0
9
0
0
9
34
0
9
0
0
0
9
0
0
9
% Q
% Arg:
9
0
9
0
0
9
0
9
0
0
9
0
9
17
9
% R
% Ser:
34
0
9
25
0
0
0
17
25
0
17
0
9
9
9
% S
% Thr:
0
0
0
0
0
0
9
0
0
17
0
0
25
0
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
34
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _